Requests is Python's most popular HTTP library. Example with Proxied:
import requests
proxies = { 'http': 'socks5h://gateway.proxied.com:1080',
'https': 'socks5h://gateway.proxied.com:1080' }
r = requests.get('https://example.com', proxies=proxies, timeout=20)
print(r.status_code, len(r.content))
The socks5h scheme sends DNS over the proxy, fully masking your target domains. Combine Requests with Proxied rotation logic to iterate geos or refresh IPs after any 429/403 response.